Kutentha Kwambiri kwa Khansa ya Pancreatic: Nkhani ndi Kafukufuku wa Chithandizo cha Khansa ya Pancreatic

Khansa ya kapamba ali ndi khansa yambiri komanso matenda ake sali bwino. Mu ntchito zachipatala, odwala ambiri amapezeka ali pamlingo wapamwamba, ndipo opaleshoni yawo ndi yochepa ndipo palibe njira zina zapadera zochizira. Kugwiritsa ntchito HIFU kungachepetse bwino kuchuluka kwa chotupa, kuchepetsa ululu, motero kutalikitsa moyo wa wodwalayo ndikuwonjezera moyo wabwino.

Mbiri ya Hyperthermiakwa zotupa zitha kutsatiridwazaka 5,000 zapitazoku Igupto wakale, ndi zolemba m'malemba akale a ku Igupto zomwe zimafotokoza kugwiritsa ntchitokutentha pochiza zotupa za m'mawere.Woyambitsa wachithandizo cha kutentha, Hippocrates, amene amaonedwa kuti ndiye bambo wa mankhwala akumadzulo, anakhalapo zaka pafupifupi 2,500 zapitazo.

Hyperthermia ndi njira yochizira yomwe imaphatikizapo kugwiritsa ntchito magwero osiyanasiyana otenthetsera(monga ma radiofrequency, microwave, ultrasound, laser, ndi zina zotero)kuti kuwonjezere kutentha kwa minofu ya chotupa kufika pamlingo wothandiza wochiritsira. Kukwera kwa kutentha kumeneku kumabweretsa kufa kwa maselo a chotupa pamene kumachepetsa kuwonongeka kwa maselo abwinobwino.

Mu 1985, bungwe la US FDA linapereka satifiketi ya opaleshoni, chithandizo cha radiation, chemotherapy, Hyperthermia, ndi immunotherapy.njira zisanu zothandiza zochizira khansa, zomwe zikuyimira njira yatsopano komanso yothandiza.

Mfundo yaikulu ndikugwiritsa ntchito mphamvu zakuthupi kutentha thupi lonse kapena malo enaake a thupi, kukweza kutentha kwa minofu ya chotupa kufika pamlingo wothandiza wochiritsira ndikuchisunga kwa nthawi inayake. Mwa kugwiritsa ntchito mwayi wosiyana kwa kulekerera kutentha pakati pa minofu yabwinobwino ndi maselo a chotupa, cholinga chake ndi kukwaniritsa cholinga choyambitsa apoptosis ya maselo a chotupa popanda kuwononga minofu yabwinobwino.

Nkhani Yoyamba Yokhudza Chithandizo cha Khansa ya Pancreatic:

Wodwala: Mkazi, wazaka 46, chotupa m'chimake cha kapamba

M'mimba mwake mwa chotupacho muli 34mm (anteroposterior), 39mm (transverse), ndi 25mm (craniocaudal). Pambuyo pa chithandizo cha kutentha chotsogozedwa ndi ultrasound,MRI yotsatira inasonyeza kuti chotupa chachikulu chinali chitachotsedwa ntchito.

Nkhani Yachiwiri Yokhudza Chithandizo cha Khansa ya Pancreatic:

Wodwala: Mkazi, wazaka 56, khansa ya kapamba yokhala ndi matenda ambiri a chiwindi

Chithandizo chofanana cha matenda a kapamba ndi chiwindi omwe amafalikira nthawi imodzi pogwiritsa ntchito njira ya ultrasound yotsogozedwa ndi kutentha.MRI yotsatira inasonyeza kuti chotupacho sichinagwire ntchito, ndipo m'mbali mwake munali momveka bwino komanso molondola.

Nkhani 3 Yothandizira Khansa ya Pancreatic:

Wodwala: Mwamuna, wazaka 54, khansa ya kapamba

Ululu umatha kwathunthu mkati mwa masiku awiripambuyo pa chithandizo cha HIFU (high-intensity focused ultrasound).Chotupacho chinachepa ndi 62.6% pa masabata 6, 90.1% pa miyezi itatu, ndipo milingo ya CA199 inabwerera mwakale pa miyezi 12.

Nkhani 4 Yothandizira Khansa ya Pancreatic:

Wodwala: Mkazi, wazaka 57, khansa ya kapamba

Kutupa kwa chotupa kunachitika patatha masiku atatu kuchokera pamene chithandizo cha HIFU chinayamba.Chotupacho chinachepa ndi 28.7% pa masabata 6, 66% pa miyezi itatu, ndipo ululu unachepa kwathunthu.

Nkhani 5 Yokhudza Chithandizo cha Khansa ya Pancreatic:

Wodwala: Mkazi, wazaka 41, khansa ya kapamba

Pambuyo pa masiku 9 a chithandizo cha HIFU,Kufufuza kotsatira kwa PET-CT kunawonetsa necrosis yayikulu pakati pa chotupacho.

Nkhani 6 Yokhudza Chithandizo cha Khansa ya Pancreatic:

Wodwala: Mwamuna, wazaka 69, khansa ya kapamba

Kujambula kwa PET-CT kotsatira theka la mwezi pambuyo pa chithandizo cha HIFUadawonetsa kutha kwathunthu kwa chotupacho, palibe kutengedwa kwa FDG, ndipo pambuyo pake kuchepa kwa milingo ya CA199.

Nkhani 7 Yokhudza Chithandizo cha Khansa ya Pancreatic:

Wodwala: Mkazi, wazaka 56, khansa ya kapamba

Kujambula kwa CT kotsatira tsiku limodzi pambuyo pa chithandizo cha HIFU kunawonetsa80% kuchotsa chotupa.

Nkhani 8 Yokhudza Chithandizo cha Khansa ya Pancreatic:

Wazaka 57, khansa ya kapamba

Pambuyo pa chithandizo cha HIFU, CT scan yotsatira idzachitika.kunavumbulutsa kuchotsa kwathunthu pakati pa chotupacho.