Pa Epulo 21, 2026, Center for Drug Evaluation (CDE) ya National Medical Products Administration idalengeza kuti HS-20093 yoti igwiritsidwe ntchito pobayira jakisoni (risvutatug rezetecan) yasankhidwa kukhala Breakthrough Therapy yochizira odwala omwe ali ndi khansa ya prostate yosagonjetsedwa ndi kudulidwa omwe adalandira kale chithandizo chatsopano cha mahomoni ndi mankhwala a chemotherapy ochokera ku taxane. Nkhaniyi imabweretsa chiyembekezo chatsopano kwa odwala khansa ya prostate padziko lonse lapansi.
HS-20093 (HS-20093 / GSK5764227) ndi mankhwala olimbana ndi ma antibody-drug conjugate (ADC) a B7-H3 omwe adapangidwa pawokha ndi Hansoh. Pa 2026 American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU 2026), zotsatira kuchokera ku mayeso otseguka, a multicenter Phase II otchedwa ARTEMIS-003 (NCT06001255) zidaperekedwa mwalamulo. Kafukufukuyu adawunika momwe HS-20093 imagwirira ntchito komanso chitetezo chake mwa odwala omwe ali ndi khansa ya prostate yolimbana ndi metastatic castration (mCRPC) omwe adapita patsogolo atatha chithandizo chamankhwala kamodzi m'mbuyomu.
Zotsatira zake zinali zolimbikitsa:
- **Mwa odwala omwe adalandira chithandizo cha taxanes:** kutsimikizika kwa mlingo woyankha mwachidwi (cORR) kunali 38.9%, ndipo kuchuluka kwa mayankho a prostate-specific antigen (PSA) (≥50% kuchepa) kunali 40.7%.
- **Mwa odwala omwe sanalandire chithandizo cha taxanes kale:** mlingo wosatsimikizika wa yankho lolunjika (uORR) unali 41.7%, ndipo mlingo wa yankho la PSA50 unali 23.8%.
Deta iyi ikusonyeza kuti HS-20093 ikuwonetsa ntchito yolimba komanso yotsutsana ndi chotupa mosasamala kanthu za mankhwala a chemotherapy omwe adagwiritsidwa ntchito kale. Kwa odwala omwe ali ndi matenda opitilira omwe ayamba kukana kapena kubwereranso pambuyo pa chithandizo chamankhwala chamakono (mankhwala atsopano a mahomoni + chemotherapy), mosakayikira izi zikuyimira njira yatsopano komanso yothandiza kwambiri.
**Kodi odwala ochokera kumayiko ena angapeze bwanji chithandizo chamakonochi?**
Ngati inu kapena wachibale wanu mukulimbana ndi khansa ya prostate yosatha kudulidwa ndipo simukukhutira ndi njira zomwe zilipo kale kapena simukuvomereza njira zina zothandizira, tsopano mutha kufunsa ku International Department of Beijing South Region Oncology Hospital kuti muwone ngati mukuyenerera kulandira chithandizo cha HS-20093. Monga bungwe lapadera lomwe lingathe kupereka chithandizo chamankhwala chapadziko lonse lapansi, International Department ya chipatalachi yadzipereka kupereka chisamaliro chokwanira cha khansa kwa odwala padziko lonse lapansi, kuphatikizapo mwayi wopeza mayeso azachipatala atsopano komanso njira zochizira zatsopano.
**Lumikizanani nafe tsopano:**
- **Nambala ya Foni:** 400-880-3716
- **Chizindikiro cha WeChat:** 17801183037
- **Imelo:**
① 100085_010@163.com
② myimmnet@163.com
**Mfundo Zofunika:**
- Odwala ochokera kumayiko ena asanapite, ayenera kukonzekera zomasulira zachipatala zakale mu Chingerezi/Chitchaina (kuphatikizapo malipoti a matenda, mayeso ojambula zithunzi, ndi zolemba za mankhwala a chemotherapy ndi mahomoni) kuti athandize dokotala kuwunika mwachangu.
- Dipatimenti yathu yapadziko lonse lapansi ingathandize ndi makalata oyitanira visa yachipatala, nthawi yokumana, ndi ntchito zomasulira. Ngati mukufuna kudziwa zambiri, chonde titumizireni uthenga kudzera m'njira zomwe zili pamwambapa.
Nthawi yotumizira: Epulo-28-2026