SHR-A1811 ku China: Ndemanga Yofunika Kwambiri ya Khansa ya HER2+ ya m'matumbo

Polimbana ndi vuto la chithandizo cha khansa ya m'matumbo ya HER2-positive, tikumvetsa bwino chikhumbo chanu chachangu cha njira zochizira zogwira mtima komanso zapamwamba. Lero, tikubweretsa nkhani zazikulu zolimbikitsa kuchokera ku gawo la khansa ku China.

**Chithandizo Chopambana Chikupezeka: SHR-A1811 Ikuwonetsa Kuthekera Kwapadera**

Pa Januwale 28, 2025, Center for Drug Evaluation (CDE) ya China's National Medical Products Administration idalengeza kuti SHR-A1811, mankhwala atsopano opangidwa ndi Hengrui Pharma (ADC) omwe adapangidwa payokha, aperekedwa kuti awunikenso. Cholinga chake ndi kuchiza odwala akuluakulu omwe ali ndi khansa ya m'matumbo ya HER2 omwe adalephera kulandira chithandizo cham'mbuyomu ndi oxaliplatin, fluorouracil, ndi irinotecan. Izi ndi gawo lofunikira kwambiri pakugwiritsa ntchito kwake kuchipatala cha khansa ya m'matumbo ya matumbo, zomwe zikupereka chiyembekezo chatsopano kwa odwala omwe agwiritsa ntchito njira zochiritsira zodziwika bwino.

Popeza adawonetsa kale kuti ali ndi mphamvu yabwino kwambiri, mankhwalawa adavomerezedwa ku China mu Meyi 2025 pa khansa ya m'mapapo ya HER2-mutant non-small cell, kukhala mankhwala oyamba opangidwa paokha ku China a ADC ovomerezeka m'derali. Tsopano, deta yake yachipatala ya khansa ya m'matumbo ikulonjezanso: malinga ndi zotsatira za mayeso azachipatala a Gawo 1 omwe adaperekedwa ku European Society for Medical Oncology (ESMO) Congress, pa mlingo wovomerezeka, chiŵerengero cha yankho loyenera (ORR) chinafika pa 46.9%, ndipo chiŵerengero cha kupulumuka chopanda kupita patsogolo kwa miyezi 6 chinali chokwera kufika pa 85.5% mwa odwala omwe ali ndi khansa ya m'matumbo ya HER2-positive. Deta iyi ikuwonetsa kuthekera kwakukulu kwa kusintha kwa kupulumuka kwa odwala omwe ali ndi khansa ya m'matumbo ya HER2-positive.

**N’chifukwa Chiyani Muyenera Kusankha Dipatimenti Yapadziko Lonse ya Chipatala cha Oncology ku Beijing South Region?**

Poganizira za kupita patsogolo kwa ukadaulo wazachipatala ku China, momwe mungapezere chithandizo chamakonochi mosamala, mwachangu, komanso moyenera ndi nkhani yofunika kwambiri kwa odwala ochokera kumayiko ena. Dipatimenti Yapadziko Lonse ya Chipatala cha Oncology ku Beijing South Region idakhazikitsidwa chifukwa cha izi:

1. **Njira Yachangu Yopezera Mankhwala Otsogola:** Timawunika mosamala zomwe zavomerezedwa posachedwapa ndi kafukufuku wa zamankhwala ku China. Tikhoza kuwunika ndikupatsa odwala oyenerera ochokera kumayiko ena mwayi wopeza njira zamakono zochiritsira.
2. **Ntchito Zokwanira Padziko Lonse:** Kuyambira kufunsira kwa akatswiri azachipatala ndi kumasulira ndi kuwunika zolemba zachipatala m'zilankhulo ziwiri (Chitchaina-Chingerezi) mpaka kukonza makalata oitanira visa, kutsatiridwa ndi chithandizo chapadera cha "kamodzi kokha" panthawi yogonekedwa kuchipatala, chithandizo cha moyo watsiku ndi tsiku, komanso kutsatira pambuyo potuluka kuchipatala, timapereka chithandizo chokwanira komanso chapadera kuti titsimikizire kuti ulendo wachipatala ku China ndi wosavuta komanso wopanda nkhawa.
3. **Gulu Lapamwamba la Zachipatala ndi Malo Ozungulira:** Chipatalachi chimabweretsa pamodzi akatswiri odziwika bwino a khansa ochokera ku China konse, okhala ndi ukadaulo wapamwamba wofufuza matenda ndi chithandizo. Timaperekanso malo ogona odwala padziko lonse lapansi komanso malo ochiritsira odwala, kuonetsetsa kuti chisamaliro chikuperekedwa mwaluso komanso mwachifundo.

**Lumikizanani Nafe Tsopano Kuti Muyambe Ulendo Wanu wa Chiyembekezo**

Timamvetsetsa kufunika kokhala ndi nthawi yokwanira pochiza khansa. Ngati inu kapena wokondedwa wanu mukukumana ndi khansa ya m'matumbo ya HER2 kapena mavuto ena a khansa ndipo mukufuna kudziwa zambiri za SHR-A1811 kapena njira zina zamakono zochiritsira, chonde musazengereze kutilumikiza nthawi yomweyo kudzera munjira zotsatirazi:

- Nambala Yothandizira Utumiki: 400-880-3716

**Njira Zina Zosavuta Zolumikizirana:**
- **WeChat:** Chonde onjezani ID `17801183037`. Ogwirizanitsa athu azachipatala apereka chithandizo cholumikizirana pa intaneti nthawi yomweyo.
- **Imelo:**
- 100085_010@163.com
- myimmnet@163.com
Mungatumize chidule cha zachipatala chanu ndi malipoti oyenerera a mayeso ku ma adilesi a imelo omwe ali pamwambapa, ndipo tidzakonza zoti akatswiri ayambe kuwunika.

Kupita patsogolo kulikonse kwaukadaulo kumadzetsa chiyembekezo chatsopano kwa miyoyo yambiri. Dipatimenti Yapadziko Lonse ya Chipatala cha Oncology ku Beijing South Region yadzipereka kukhala mnzanu wodalirika polimbana ndi matenda, popereka ukatswiri wazachipatala komanso ntchito zabwino zapadziko lonse lapansi.

**Dipatimenti Yapadziko Lonse ya Chipatala cha Oncology ku Beijing South Region: Kuyenda ndi Dziko Lonse, Kuteteza Moyo.**