Pa Epulo 17, 2025, Hansoh Pharmaceutical yalengeza kuti mankhwala a B7-H3-target antibody-drug conjugate (ADC) HS-20093 omwe adapangidwa okha ndi gululi kuti agwiritsidwe ntchito jakisoni avomerezedwa kuti aphatikizidwe ngati mankhwala opangidwa ndi Breakthrough-Therapy ndi National Medical Products Administration (NMPA) ya ku China, ndi chizindikiro chomwe chikuyembekezeredwa cha khansa ya m'mapapo yopanda maselo ang'onoang'ono (NSCLC) yomwe ili patsogolo kapena yofalikira m'deralo popanda kusintha kwa ma driver, idapitilira kapena kubwereranso pambuyo pa platinum-based chemotherapy.
HS-20093 ndi ADC yofufuza ya B7-H3 yopangidwa ndi antibody yathunthu ya anti-B7-H3 monoclonal yolumikizidwa ndi topoisomerase inhibitor (TOPOi) ndipo imapangidwa kuti igwiritsidwe ntchito pochiza khansa ya m'mapapo, sarcoma, khansa ya mutu ndi khosi ndi zotupa zina zolimba m'mayesero angapo azachipatala ku China, ndipo gawo lalikulu kwambiri lofufuzira ndi mayeso azachipatala a Phase Ⅲ.
Kusankhidwa kumeneku kumathandizidwa ndi deta yoyambirira yachipatala kuchokera ku kafukufuku wa ARTEMIS-001. Iyi ndi njira yopitilira yoyesera ya gawo loyamba, yotseguka, yapakati pa odwala oposa 300 omwe akuwunika chitetezo, kulekerera, ndi ntchito yoyambirira yolimbana ndi chotupa mu chotupa chapamwamba kapena chofalikira m'malo ozungulira (khansa ya m'mapapo yapakhungu yopanda maselo ang'onoang'ono kapena yofalikira popanda kusintha kwa masinthidwe, yomwe idapitilira kapena kubwereranso pambuyo pa chemotherapy yochokera ku platinum), yochitidwa ndi Hansoh Pharma.
M'mbuyomu, HS-20093 idavomerezedwa kuti iphatikizidwe ngati Mankhwala Opangidwa ndi Breakthrough-Therapy ndi NMPA pazifukwa ziwiri:
·Khansa ya m'mapapo ya maselo ang'onoang'ono (ES-SCLC) yomwe imayamba pambuyo pa chithandizo choyamba (platinum doublet chemotherapy pamodzi ndi immuno-therapy).
·Osteosarcoma mwa odwala omwe apita patsogolo pa njira ziwiri zochiritsira kale.
Pakadali pano, pali mayesero ambiri azachipatala a ukadaulo watsopano wothana ndi khansa ku China omwe akufuna odwala. Mukafunsira mankhwala ndi ukadaulo watsopano, mutha kulumikizana ndi Dipatimenti Yapadziko Lonse ya Chipatala cha Oncology ku Beijing South Region.
Nambala ya Foni: 4008803716
Email：myimmnet@163.com
Nthawi yotumizira: Epulo-22-2025