Chithandizo Chachisanu cha Zotupa - Hyperthermia
Ponena za chithandizo cha chotupa, anthu nthawi zambiri amaganiza za opaleshoni, chemotherapy, ndi chithandizo cha radiation. Komabe, kwa odwala khansa omwe ali ndi gawo lotsogola omwe ataya mwayi wochita opaleshoni kapena omwe amaopa kusalolera kwa chemotherapy kapena nkhawa zokhudzana ndi radiation kuchokera ku chithandizo cha radiation, njira zawo zochiritsira komanso nthawi yopulumuka zitha kukhala zochepa.
Kuchuluka kwa kutentha kwa thupi, kuwonjezera pa kugwiritsidwa ntchito ngati mankhwala ochiritsira okha a zotupa, kungaphatikizidwenso ndi chemotherapy, radiation therapy, mankhwala achikhalidwe achi China, ndi mankhwala ena kuti apange mgwirizano wachilengedwe. Kumawonjezera chidwi cha odwala ku chemotherapy, radiation therapy, ndi mankhwala achikhalidwe achi China, zomwe zimapangitsa kuti maselo otupa a khansa achotsedwe bwino. Kuchuluka kwa kutentha kwa thupi kumawongolera moyo wa odwala ndikuwonjezera moyo wawo pamene amachepetsa zotsatirapo zoyipa zomwe zimayambitsidwa ndi radiation therapy ndi chemotherapy. Chifukwa chake, amatchedwa"Chithandizo chobiriwira"ndi gulu lachipatala lapadziko lonse lapansi.
Dongosolo la RF8 Hyperthermia Lokhala ndi Mafunde a Magetsi Othamanga Kwambiri
THERMOTRON-RF8ndi njira yochepetsera kutentha kwa thupi yopangidwa limodzi ndi Japan National Institute of Science and Technology, Kyoto University School of Medicine, ndi Yamamoto VINITA Corporation.
*RF-8 ili ndi zaka zoposa 30 zokumana nazo zachipatala.
*Imagwiritsa ntchito ukadaulo wapadera wa mafunde amagetsi a 8MHz padziko lonse lapansi.
*Kachitidwe kake kowongolera kutentha kali ndi malire olakwika osakwana +(-) madigiri Celsius 0.1.
Dongosololi limayendetsa bwino mphamvu ya mafunde amagetsi popanda kufunikira chitetezo chamagetsi.
Imagwiritsa ntchito kapangidwe kothandiza kothandizidwa ndi kompyuta pokonzekera chithandizo ndikuwunika panthawi ya chithandizo.
Zizindikiro za hyperthermia:
Mutu ndi Khosi, Ziwalo:Ziphuphu za mutu ndi khosi, zotupa za mafupa zoopsa, zotupa za minofu yofewa.
Khomo la Chifuwa:Khansa ya m'mapapo, khansa ya m'mero, khansa ya m'mawere, mesothelioma yoopsa, ndi lymphoma yoopsa.
Mphuno ya m'chiuno:Khansa ya impso, khansa ya chikhodzodzo, khansa ya prostate, khansa ya m'matumbo, khansa ya m'mimba, khansa ya pachibelekero, khansa ya endometrial, khansa ya m'chiberekero.
M'mimba:Khansa ya chiwindi, khansa ya m'mimba, khansa ya kapamba, khansa ya m'matumbo.
Ubwino wa Hyperthermia Pophatikizana ndi Mankhwala Ena:
Kutentha kwambiri:Mwa kutentha minofu yozama m'dera lomwe mukufuna kufika madigiri Celsius 43, mapuloteni amachepa m'maselo a khansa. Mankhwala ambiri angayambitse apoptosis ya maselo a khansa ndikusintha malo am'deralo komanso kagayidwe kachakudya, zomwe zimapangitsa kuti mapuloteni ndi ma cytokine azitha kutentha kwambiri, motero kumawonjezera mphamvu ya chitetezo chamthupi.
Kutentha Kwambiri + Chemotherapy (Yoperekedwa ndi Mitsempha):Pogwiritsa ntchito gawo limodzi mwa magawo atatu mpaka theka la mlingo wa chemotherapy wamba, kupereka mankhwala kudzera m'mitsempha kumachitika pamene kutentha kwa thupi kufika madigiri 43 Celsius. Izi zimawonjezera kuchuluka kwa mankhwala am'deralo komanso kugwira ntchito bwino komanso kuchepetsa zotsatira zoyipa za chemotherapy. Itha kuyesedwa ngati njira ya chemotherapy "yochepetsa poizoni" kwa odwala omwe sali oyenera chemotherapy yachikhalidwe chifukwa cha matenda awo.
Kutentha Kwambiri ndi Kutuluka kwa Mafuta (Kutuluka kwa Chifuwa ndi M'mimba):Kuchiza matenda a khansa okhudzana ndi khansa ndi kutuluka kwa magazi m'mimba n'kovuta. Mwa kuchita nthawi yomweyo kutentha kwambiri ndi kutulutsa mankhwala a chemotherapeutic kudzera m'machubu otulutsira madzi, maselo a khansa amatha kuwonongedwa, kuchepetsa kuchulukana kwa madzi m'thupi ndikuchepetsa zizindikiro za wodwalayo.
Kutenthetsa Kwambiri ndi Kuchiritsa kwa Radiation:Chithandizo cha radiation sichigwira ntchito bwino polimbana ndi maselo omwe ali mu gawo la S, koma maselowa sakhudzidwa ndi kutentha. Mwa kuphatikiza kutentha kwambiri mkati mwa maola anayi chithandizo cha radiation chisanachitike kapena chitatha, chithandizo chingatheke kwa maselo onse omwe ali pamlingo wosiyana wa selo tsiku lomwelo, zomwe zimapangitsa kuti pakhale kuchepa kwa 1/6 kwa mlingo wa radiation.
Mfundo ndi Chiyambi cha Chithandizo cha Hyperthermia
Mawu akuti “Hyperthermia” amachokera ku liwu lachi Greek, lotanthauza “kutentha kwambiri” kapena “kutentha kwambiri.” Limatanthauza njira yochizira yomwe magwero osiyanasiyana a kutentha (radiofrequency, microwave, ultrasound, laser, ndi zina zotero) amagwiritsidwa ntchito kuti akweze kutentha kwa minofu ya chotupa kufika pamlingo wothandiza wochiritsira, zomwe zimapangitsa kuti maselo a chotupa afe pomwe maselo abwinobwino asawonongeke. Hyperthermia sikuti imangopha maselo a chotupa komanso imasokoneza kukula ndi kubereka kwa maselo a chotupa.
Woyambitsa hyperthermia akhoza kutsatiridwa kubwerera ku Hippocrates zaka 2500 zapitazo. Chifukwa cha chitukuko cha nthawi yayitali, milandu ingapo yalembedwa mu zamankhwala amakono komwe zotupa zinatha odwala atadwala malungo aakulu. Mu 1975, pa Msonkhano Wapadziko Lonse pa Hyperthermia womwe unachitikira ku Washington, DC, hyperthermia inadziwika ngati njira yachisanu yothandizira zotupa zoopsa.Idalandira satifiketi ya FDA mu 1985.Mu 2009, Unduna wa Zaumoyo ku China unatulutsa chikalata cha “Management Specification for Local Tumor Hyperthermia and New Technologies,” chomwe chinalimbitsa kutentha kwa thupi ngati njira imodzi yofunika kwambiri yothandizira khansa, kuphatikizapo opaleshoni, chithandizo cha radiation, chemotherapy, ndi immunotherapy.
Kuwunikanso Nkhani
Nkhani 1: Wodwala amene ali ndi vuto la chiwindi chifukwa cha khansa ya maselo a impsoadapatsidwa chithandizo cha immunotherapy kwa zaka ziwiri ndipo adalandira magawo 55 ophatikizana a hyperthermia. Pakadali pano, kujambula zithunzi kukuwonetsa kutha kwa zotupa, zizindikiro za chotupa zatsika kufika pamlingo wabwinobwino, ndipo kulemera kwa wodwalayo kwakwera kuchoka pa mapaundi 110 kufika pa mapaundi 145. Akhoza kukhala ndi moyo wabwinobwino.
Nkhani yachiwiri: Wodwala yemwe ali ndi pulmonary mucinous adenocarcinomaadakumana ndi kupita patsogolo kwa matenda atachitidwa opaleshoni, chithandizo cha radiation, chithandizo cholunjika, ndi chithandizo cha immunotherapy. Khansayo inali ndi kufalikira kwakukulu kwa pleural effusion. Kuwonjezeka kwa ion therapy pamodzi ndi chithandizo chapamwamba cha immunotherapy kunayambitsidwa milungu itatu yapitayo. Chithandizochi sichinawonetse zotsatirapo zoyipa, ndipo wodwalayo alibe vuto lalikulu. Chithandizochi chikuyimira mwayi womaliza wa wodwalayo.
Nkhani 3: Wodwala khansa ya m'matumbo atachitidwa opaleshoniomwe anayenera kusiya chithandizo cholunjika chifukwa cha kuwonongeka kwakukulu kwa khungu. Atamaliza gawo limodzi la chithandizo cha ion chothamanga kwambiri, wodwalayo adapeza 11kulemera kwa mapaundi.
Nthawi yotumizira: Ogasiti-04-2023