Kusindikiza kwaposachedwa kwa World Health Organisation's Classification of Soft Tissue and Bone Tumors, yomwe idasindikizidwa mu Epulo 2020, imayika.sarcomam'magulu atatu: szotupa zambiri za minofu, zotupa za m'mafupa, ndi zotupa za fupa ndi minyewa yofewa yokhala ndi ma cell ang'onoang'ono ozungulira osasiyanitsidwa.(monga EWSR1-non-ETS fusion round cell sarcoma).
"Cancer Yoyiwalika"
Sarcoma ndi mtundu wosowa wakhansa mwa akuluakulu, kuwerengera pafupifupi1%a khansa onse akuluakulu, omwe nthawi zambiri amatchedwa "Cancer Yoiwalika."Komabe, ndi pang'onowamba mwa ana, kuwerengera zozungulira15% mpaka 20%za khansa zonse zaubwana.Zitha kuchitika m'mbali iliyonse ya thupi, nthawi zambiri m'thupimanja kapena miyendo(60%), kutsatiridwa ndithunthu kapena pamimba(30%), ndipo pomalizamutu kapena khosi(10%).
M'zaka zaposachedwa, kuchuluka kwa zotupa za mafupa ndi zofewa zakhala zikuwonjezeka pang'onopang'ono.Matenda owopsa a mafupa owopsa amapezeka kwambiri kwa achinyamata ndi azaka zapakati ndipo amaphatikizapo osteosarcoma, Ewing sarcoma, chondrosarcoma, malignant fibrous histiocytoma, ndi chordoma, pakati pa ena.Matenda owopsa a minofu yofewa ndi monga synovial sarcoma, fibrosarcoma, liposarcoma, ndi rhabdomyosarcoma.Ma metastases a mafupa amapezeka kwambiri mwa anthu azaka zapakati komanso okalamba, omwe ali ndi zotupa zoyamba kukhala khansa ya m'mapapo, khansa ya m'mawere, khansa ya impso, khansa ya prostate, ndi khansa ya chithokomiro, pakati pa ena.
Kuzindikira Koyambirira, Kuchiza Moyambirira - Kuwunikira "Zotupa" Zobisika
Chifukwa chakuchulukirachulukira kwa ma sarcoma, zotupa zambiri zimakhala ndi matenda osadziwika bwino asanayambe kuchitidwa opaleshoni ndipo alibe kuyezetsa mwatsatanetsatane.Izi nthawi zambiri zimabweretsa kutulukira panthawi ya opaleshoni kuti chotupacho sichiri chophweka monga momwe akuyembekezeredwa asanachite opaleshoni, zomwe zimapangitsa kuti asakwaniritsidwe.Kubwereza kwa postoperative kapena metastasis kumatha kuchitika, kupangitsa odwala kuphonya mwayi wopeza chithandizo choyenera.Chifukwa chake,kuzindikiridwa msanga, kuyezetsa kolondola, ndi chithandizo chanthawi yake kumakhudza kwambiri momwe odwala amathandizira. Lero, tikufuna kukudziwitsani katswiri wina wolemekezeka yemwe ali ndi zaka pafupifupi 20pakuzindikiritsa kokhazikika komanso chithandizo chamunthu payekha cha minofu yofewa ya sarcoma, ndipo amayamikiridwa kwambiri ndi makampani ndi odwala -DokotalaLiu Jiayongkuchokera ku dipatimenti ya Bone and Soft Tissue ku Peking University Cancer Hospital.
Kuvumbulutsa Katswiri Wodziwa Mwakuya Pamafupa ndi Ululu Wanyama - Dr.Liu Jiayong
Dokotala wa Zamankhwala, Dokotala Wamkulu, Pulofesa Wothandizira.Anaphunzira ku Anderson Cancer Center ku United States.
Katswiri:Chithandizo chokwanira cha sarcoma ya minofu yofewa (kuchotsa opaleshoni ndi kumanganso; chemotherapy, chithandizo chamankhwala, ndi immunotherapy);opaleshoni mankhwala a melanomas.
Pokhala ndi zaka pafupifupi 20 zachipatala, Dokotala Liu Jiayong wapeza ukadaulo wambiri wamankhwala ndi maopaleshoni.kuzindikiridwa kokhazikika ndi mapulani amunthu payekhapayekhakwa sarcoma zofewa wamba monga undifferentiated pleomorphic sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, adenocystic carcinoma-like sarcoma, epithelioid sarcoma, fibrosarcoma, angiosarcoma, ndi infiltrative fibromatosis.Iye ali makamakawodziwa kugwira ntchito ndi mitsempha ya magazi ndi mitsempha panthawi yochotsa ziwalo za sarcoma, komanso kukonza ndi kukonzanso zowonongeka za minofu yofewa pakhungu.Dokotala Liu amamvetsera moleza mtima kwa wodwala aliyense, amafunsa mosamala za mbiri yake yachipatala, ndipo amalemba mosamala zachipatala.Amapereka chidwi chapadera pa kusintha kwa mkhalidwe wa wodwalayo pazigawo zosiyanasiyana za nthawi, monga opaleshoni isanayambe komanso itatha, panthawi ya chithandizo, kutsata, ndi kupitirira kwa matenda, kupanga ziganizo zolondola komanso kusintha kwa nthawi yake kwa mapulani a chithandizo.
Dokotala Liu Jiayong pano ndi membala wa Soft Tissue Sarcoma ndi Melanoma Gulu la Chinese Anti-Cancer Association, komanso membala wa Bone Tumor Group of the Beijing Society of Orthopedics of the Chinese Medical Association.Mu 2010, iye anali woyamba ku China kumasulira ndi kufalitsa "NCCN Clinical Practice Guidelines in Soft Tissue Sarcoma," kulimbikitsa chithandizo chokwanira chokwanira cha sarcoma ya minofu yofewa.Akupitirizabe kuyesetsa kuti apite patsogolo mu kafukufuku wachipatala ndi sayansi, ngakhale kuti ali ndi katundu wambiri wodwala.Iye ndi wodzipereka komanso wodalirika kwa wodwala aliyense yemwe amamuchiritsa, ndipo panthawi ya mliriwu, adathana ndi zovuta zomwe odwala omwe amapeza chithandizo chamankhwala poyankha mwachangu kukaonana ndi odwala, kuwunikanso zotsatira zotsatila, ndikupereka malingaliro oyenera a chithandizo kudzera pamapulatifomu ochezera pa intaneti monga. Gulu la Odwala la Dokotala Wabwino.
Nkhani Yaposachedwa
Bambo Zhang, wodwala wazaka 35, mwadzidzidzi adataya masomphenya kumayambiriro kwa chaka cha 2019. Pambuyo pake, adachitidwa opaleshoni ya kumanzere ya enucleation chifukwa cha kuwonjezeka kosalekeza kwa intraocular pressure.The postoperative pathology anasonyeza kutupa pseudotumor.M'chilimwe cha chaka chomwecho, tinthu tating'onoting'ono ta m'mapapo tinapezeka pakuwunika kotsatira, koma palibe maselo otupa omwe adapezeka kudzera mu singano.Kuwunikanso kwina kunawonetsa ma metastases ambiri a mafupa ndi mapapo.Kukambitsirana kwa zipatala zam'deralo ndi zapamwamba zidamupeza ndi chotupa chotupa cha myofibroblastic.Mu Ogasiti 2022, adalandira mankhwala amphamvu kwambiri a chemotherapy, omwe adachepetsa ululu wake koma sanawonetse kusintha kowoneka bwino kwa zotupazo ataunikanso.Mkhalidwe wake wakuthupi unafookanso.Ngakhale zinali choncho, banja lake silinataye mtima.Atatha kufunafuna malingaliro angapo, adabwera kwa Dokotala Liu Jiayong mu November 2022. Pambuyo poyang'anitsitsa mbiri yachipatala ya wodwalayo, zolemba zonse zachipatala, mayesero a matenda, ndi deta yojambula,DokotalaLiu anapempha mankhwala a chemotherapy okhala ndi mlingo wochepa wa methotrexate ndi Changchun Ruibin.Mankhwala a chemotherapy awa ndiwotsika mtengo ndipo amakhala ndi zotsatirapo zochepa.Pambuyo pa masiku a 35 a mankhwala, CT scan yotsatila inasonyeza kuti misa ya m'mapapo abwino inali itasowa, kusonyeza kulamulira bwino kwa chotupacho.Kafukufuku wotsatira waposachedwa pachipatala cha Beijing South Region Oncology Hospital adawonetsa mapapu okhazikika, ndipo a Doctor Liu adalimbikitsa kuti aziyendera pafupipafupi.Wodwalayo ndi banja lake tsopano ali ndi chidaliro chokulirapo m’machiritso otsatira, odzazidwa ndi chiyembekezo.Iwo amaona kuti aona kuwala kwa kuwala paulendo wolandira chithandizo ndipo akusonyeza kuyamikira kwawo kochokera pansi pa mtima mwa kupereka mbendera ya silika yoyamikira.
Nthawi yotumiza: Aug-25-2023