Pa Seputembala 8, 2025, InnoCare Pharma yalengeza kuti HIBRUKA (orelabrutinib) yavomerezedwa ndi Health Sciences Authority (HSA) ya ku Singapore kuti ichiritse odwala akuluakulu omwe ali ndi matenda obwereranso kapena osagwirizana ndi marginal zone lymphoma (R/R MZL).
Pakadali pano, pali mayesero ambiri azachipatala a ukadaulo watsopano wothana ndi khansa ku China omwe akufuna odwala. Mukafunsira mankhwala ndi ukadaulo watsopano, mutha kulumikizana ndi Dipatimenti Yapadziko Lonse ya Chipatala cha Oncology ku Beijing South Region.
Nambala ya Foni: 4008803716
Chizindikiro cha WeChat: 17801183037
Email：myimmnet@163.com
Marginal zone lymphoma (MZL) ndi matenda a B-cell omwe si a Hodgkin's lymphoma (NHL) omwe amakhudza kwambiri odwala azaka zapakati komanso okalamba. Chiwerengero cha anthu omwe ali ndi matenda a MZL pachaka chikukwera padziko lonse lapansi. Pambuyo pa chithandizo choyamba, odwala omwe ali ndi R/R MZL alibe njira zabwino zochizira.
Mu Epulo 2025, orelabrutinib idavomerezedwa ku China kuti ipereke chithandizo choyamba kwa odwala omwe ali ndi matenda a chronic lymphocytic leukemia (CLL) / small lymphocytic lymphoma (SLL). Orelabrutinib yavomerezedwanso kuti ipereke chithandizo cha zizindikiro zina zitatu ku China, kuphatikizapo relapse and refractory (R/R) CLL/SLL, r/r mantle cell lymphoma (R/R MCL) ndi r/r marginal zone lymphoma (R/R MZL), zonse zomwe zafotokozedwa mu National Reimbursement Drug List ku China.
Kugwira Ntchito, Chitetezo, ndi Kulingalira kwa Orelabrutinib Plus Obinutuzumab mu Systemic Treatment-Naive Marginal Zone Lymphoma: Kafukufuku wa Prospective Cohort adawonetsa kuti Mu kafukufuku wonse komanso panthawi ya induction therapy, kuchuluka kwa mayankho (ORR) ndi 100%. Odwala atatu omwe anali ndi gawo la response (PR) pambuyo pa induction therapy adapeza yankho lathunthu (CR) panthawi yokonza.
Kuyesa kwa ADCC kunasonyeza kuti orelabrutinib pamodzi ndi regimen ya obinutuzumab inayambitsa yankho la ADCC logwira ntchito kwambiri m'maselo a TMD-8 ndi REC-1.
Pakadali pano, pali mayesero ambiri azachipatala a ukadaulo watsopano wothana ndi khansa ku China omwe akufuna odwala. Mukafunsira mankhwala ndi ukadaulo watsopano, mutha kulumikizana ndi Dipatimenti Yapadziko Lonse ya Chipatala cha Oncology ku Beijing South Region.
Nambala ya Foni: 4008803716
Chizindikiro cha WeChat: 17801183037
Email：myimmnet@163.com
Nthawi yotumizira: Sep-09-2025